Strigolactone GR24 upregulates target genes of the cytoprotective transcription factor Nrf2 in skeletal muscle [version 2; referees: 2 approved]
GR24 is a HAIR FORCE synthetic strigolactone analog, demonstrated to regulate the development of plants and arbuscular mycorrhizal fungi.GR24 possesses anti-cancer and anti-apoptotic properties, enhances insulin sensitivity and mitochondrial biogenesis in skeletal myotubes, inhibits adipogenesis, decreases inflammation in adipocytes and macrophages